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For Children With Poorly Controlled Asthma, Long-Acting Beta-Agonists Shown To Be Most Effective Step-Up Therapy

March 4, 2010 Health News No Comments

For children whose asthma is not well controlled and on low doses of inhaled corticosteroids, a long-acting beta-agonist (LABA) may be the most effective of three possible step-up treatments. National Jewish clinician-scientists Stanley Szefler, Joseph Spahn, Ronina Covar Gary Larsen and Lynn Taussig, and colleagues in the NIH-funded Childhood Asthma Research and Education Network published their findings March 2, 2010, online in the New England Journal of Medicine…

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Resequencing and copy number analysis of the human tyrosine kinase gene family in poorly differentiated gastric cancer

November 26, 2009 Gastric Obstruction No Comments

The tyrosine kinase (TK) family is an important regulator of signaling pathways that control a variety of physiological and pathological conditions, and a substantial proportion of TK genes are genetically altered in cancer. To clarify the somatic mutation profile of TK genes and discover potential targets for gastric cancer (GC) therapy, we undertook a systematic screening of mutations in the kinase domains of all human TK genes (636 exons of 90 genes) in 17 GC cell lines and 52 microdissected primary GCs with poorly differentiated histology. We identified 26 non-synonymous alterations (22 genes in total) that included 11 sequence alterations… Continue reading

Can Drug & Device Makers Innovate Themselves to Extinction?

November 25, 2009 Health News No Comments

A study of heart-attack patients published in the late 1980s was wildly successful. Researchers showed they could lower the heart-attack death rate to 8% from 13% by giving patients aspirin and a drug called streptokinase. These days, though, an 8% mortality rate would be disastrous; the rate in most studies of heart attack patients is somewhere around 4%.
That points to a challenge for companies developing new therapies for heart disease (and other well treated maladies): The better existing therapies are, the harder it is to come up with something that’s an improvement. An essay published in this week’s JAMA calls… Continue reading

Infant Mortality Rates: U.S. Ranks Poorly Among Industrialized Nations

November 4, 2009 Health News No Comments

New information released today by the Centers for Disease Control and Prevention’s National Center for Health Statistics links preterm births and infant mortality rates in the United States. The U.S. ranked 30th out of 31 countries in overall infant mortality rates, showing 6.9 of every 1,000 live births resulted in death, a statistic that is complemented by the fact that 1/8 of the births in the U.S. were preterm, a high rate compared to numbers from European countries.read more Go to Source… Continue reading

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Hazard scenarios of truck drivers’ occupational accidents on and around trucks during loading and unloading.

March 21, 2010

The objective of the present study was to establish the hazard scenarios for truck drivers during loading/unloading through analyses of text descriptions of accident processes. Focus was on accidents that were primarily related to movement/operation on and around the truck, which are particular to truck drivers. Special emphasis was placed on falls from heights, as this was shown to be the most frequent type of accident and a major cause of fractures among truck drivers. Analyses of text descriptions of 136 accidents, including 63 cases of fall from height, collected in one company over a period of three years, revealed… Continue reading

Democratic Leaders: ‘We Have The Votes’ To Pass Health Reform In Historic Vote

March 21, 2010

News organizations are reporting that Democrats are “poised” to pass sweeping health reform legislation Sunday afternoon, as President Barack Obama made an impassioned plea for the bill.

Reuters: “An upbeat House Democratic leader Steny Hoyer predicted victory in Sunday’s vote on the biggest revamp of the $2.5 trillion healthcare system in four decades, although even the most optimistic Democrats expected a razor-thin margin. ‘Clearly, we believe we have the votes,’ Hoyer told reporters. ‘We expect we have the votes to pass the Senate bill’” (Whitesides, 3/20).

The New York Times: “President Obama, in an extraordinary session with the… Continue reading

Limb loss a growing global crisis

March 20, 2010

The earthquake that rattled Haiti on Jan. 12 created as many as 6,000 instant amputees. Experts say the crisis in Hait highlights a grim reality: the number of amputees worldwide is rising — and fast. Go to Source… Continue reading

Dems: Abortion flap won’t scuttle health bill

March 20, 2010

President Barack Obama rallies House Democrats for a final health care push as party leaders appear confident they’ve overcome a flare-up within their ranks over abortion funding restrictions. Go to Source… Continue reading

Years to wait for health care no matter what?

March 20, 2010

One of our readers asked whether it’s true that the health insurance reform bill won’t take effect until four years after the president signs it into law. Msnbc.com fact-checks this claim — and more. Go to Source… Continue reading

Health Reform Crucial Weekend: Democratic Leaders Predict Victory, Abortion Still Stumbling Block

March 20, 2010

News outlets are focusing on President Barack Obama’s planned meeting with all the House Democrats today as they prepare for Sunday’s crucial vote on health care overhaul.

The Associated Press: “Obama decided to make one final, personal appeal to rank-and-file Democrats, arranging a visit to the Capitol Saturday afternoon. Republicans, unanimous in opposition to the bill, complained anew about its cost and reach. … Democratic leaders and Obama focused last-minute lobbying efforts on two groups of Democrats, 37 who voted against an earlier bill in the House and 40 who voted for it only after first making sure it would… Continue reading

Health Reform Crucial Weekend: Democratic Leaders Predict Victory, Abortion Still Stumbling Block

March 20, 2010

News outlets are focusing on President Barack Obama’s planned meeting with all the House Democrats today as they prepare for Sunday’s crucial vote on health care overhaul.

The Associated Press: “Obama decided to make one final, personal appeal to rank-and-file Democrats, arranging a visit to the Capitol Saturday afternoon. Republicans, unanimous in opposition to the bill, complained anew about its cost and reach. … Democratic leaders and Obama focused last-minute lobbying efforts on two groups of Democrats, 37 who voted against an earlier bill in the House and 40 who voted for it only after first making sure it would… Continue reading

BD Diagnostics Launches The BD Protect(TM) Infection Surveillance And Prevention Software Portfolio

March 20, 2010

BD Diagnostics, a segment of BD (Becton, Dickinson and Company), announced the launch of the BD Protect™ Infection Surveillance and Data Management System, a portfolio of healthcare management software solutions that tracks infections and helps prevent their transmission at three levels — from patient to patient, between patients and healthcare workers, and from community sources to healthcare settings…

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