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The Retrograde Aortic Arch in the Hybrid Approach to Hypoplastic Left Heart Syndrome [ORIGINAL ARTICLES: PEDIATRIC CARDIAC]

February 4, 2010 Gastric Obstruction No Comments

Conclusions
Clinically important RAAO occurred in 24% of the hypoplastic left heart syndrome patients in this series. If RAAO is detected at birth or early interstage, a Norwood operation is now favored. Palliative interventional catheterization remains very important mid and late interstage for continuing the hybrid strategy toward comprehensive stage 2. (Source: The Annals of Thoracic Surgery) Go to Source… Continue reading

Early and Intermediate Outcome After Anatomic Repair of Congenitally Corrected Transposition of the Great Arteries [ORIGINAL ARTICLES: PEDIATRIC CARDIAC]

February 1, 2010 Gastric Obstruction No Comments

Conclusions
Senning/arterial switch operations can be performed with excellent intermediate-term outcomes in patients with lesions previously thought to confer higher risk. Candidates for Senning/Rastelli procedures may be at increased risk for postoperative morbidity and mortality. More data are necessary to determine factors influencing outcome after anatomic repair. (Source: The Annals of Thoracic Surgery) Go to Source… Continue reading

Association of Interleukin-8 Gene Polymorphism With Cachexia From Patients With Gastric Cancer

Journal of Interferon & Cytokine Research , Vol. 0, No. 0: 1-10. (Source: Journal of Interferon) Go to Source… Continue reading

Importance of membrane-bound catechol-O-methyltransferase in L-DOPA metabolism: a pharmacokinetic study in two types of Comt gene modified mice

Conclusions and implications: In S-COMT-deficient mice, MB-COMT in the liver and the duodenum is able to O-methylate about one-half of exogenous L-DOPA. Sexual dimorphism and activity of the two COMT isoforms seems to be tissue specific and more prominent in peripheral tissues than in the brain. (Source: British Journal of Pharmacology) Go to Source… Continue reading

Macrophage migration inhibitory factor regulates proliferation of gastric cancer cells via the PI3K/Akt pathway.

November 26, 2009 Gastric Obstruction No Comments

CONCLUSION: Macrophage MIF increases the proliferation of gastric cancer cells, induces the expression of cyclin D1 at the transcriptional level and inhibits the expression of p27(Kip1) at the post-transcriptional level via the PI3K/Akt pathway.
PMID: 19938192 [PubMed - as supplied by publisher] (Source: World Journal of Gastroenterology : WJG) Go to Source… Continue reading

Routine modified D2 lymphadenectomy performance in pT1-T2N0 gastric cancer.

November 26, 2009 Gastric Obstruction No Comments

CONCLUSION: In gastric cancer, true R0 resection may not be achieved without modified D2 lymphadenectomy. Until D2+/D3 lymphadenectomy becomes standard, modified D2 lymphadenectomy should be performed routinely.
PMID: 19938196 [PubMed - as supplied by publisher] (Source: World Journal of Gastroenterology : WJG) Go to Source… Continue reading

Genetic and epigenetic characteristics of gastric cancers with JC virus T-antigen.

November 26, 2009 Gastric Obstruction No Comments

CONCLUSION: The results suggest that JCV T-Ag is involved in gastric carcinogenesis through multiple mechanisms of genetic and epigenetic alterations.
PMID: 19938198 [PubMed - as supplied by publisher] (Source: World Journal of Gastroenterology : WJG) Go to Source… Continue reading

Does testosterone prevent early postoperative complications after gastrointestinal surgery?

November 26, 2009 Gastric Obstruction No Comments

CONCLUSION: Patients with low testosterone level were prone to higher postoperative complications, which was evident in both sexes. However, further studies are necessary to support this result.
PMID: 19938202 [PubMed - as supplied by publisher] (Source: World Journal of Gastroenterology : WJG) Go to Source… Continue reading

Improving survival for gastric cancer patients – the role of the surgeon

November 26, 2009 Gastric Obstruction No Comments

No Abstract. (Source: Journal of Surgical Oncology) Go to Source… Continue reading

Resequencing and copy number analysis of the human tyrosine kinase gene family in poorly differentiated gastric cancer

November 26, 2009 Gastric Obstruction No Comments

The tyrosine kinase (TK) family is an important regulator of signaling pathways that control a variety of physiological and pathological conditions, and a substantial proportion of TK genes are genetically altered in cancer. To clarify the somatic mutation profile of TK genes and discover potential targets for gastric cancer (GC) therapy, we undertook a systematic screening of mutations in the kinase domains of all human TK genes (636 exons of 90 genes) in 17 GC cell lines and 52 microdissected primary GCs with poorly differentiated histology. We identified 26 non-synonymous alterations (22 genes in total) that included 11 sequence alterations… Continue reading

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We’re at Expo West!

March 12, 2010

Our whole editorial team is wandering the aisles of the Natural Products Expo West Friday through Saturday, looking for cool new products, bars, food, organics, beauty products, kids’ snacks, and more.
We’ll be tweeting live all day about the neat things we’re finding for you (hopefully posting some twitpics, too), and will be updating our blog with quirky sightings, hot trends, and the tastiest treats we find.
Join us on Twitter, Lifescript on Facebook, and Lifescript Weightloss on Facebook and let us know what products you’re looking for this year. …
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National Athletic Trainers’ Association Offers Guidelines For Parents To Ensure A Safe Environment For Youth Athletes

March 12, 2010

Parents are naturally concerned about the health and safety of their children, and that’s especially true when their children are athletes. With nearly 7 million high school students participating in sports today, there are a reported 715,000 high school sports-related injuries experienced each year, and 8,000 children are treated in emergency rooms each day for sports-related injuries.1 To reduce the risk of injury, the National Athletic Trainers’ Association (NATA) offers a number of suggestions for parents, coaches, administrators and athletes to ensure a safe and healthy environment…

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Starting on the Long Road to Accrediting a Med School

March 12, 2010

Connecticut’s Quinnipiac University announced earlier this year that it wanted to open a medical school, beginning a push that will take until 2013 or 2014 to get the first med students in the door.
The new school would be located in several buildings that the university, located near New Haven, purchased in nearby North Haven from WellPoint’s Anthem unit for $32 million several years ago. Read more on the plans here.
Schools like Quinnipiac that want to grant MD degrees go through a lengthy process required by the Liaison Committee on Medical Education. The panel is made up of med-school officials, practicing… Continue reading

Heart Disease And Stroke Survivors Urge Congress To Increase Funding For The National Institutes Of Health

March 12, 2010

Enhance National Institutes of Health (NIH)-supported research to improve health, spur economic growth and innovation and science. American Heart Association patient advocates and researchers today delivered that message to members of Congress during the association’s Research Saves Lives Fly-In Lobby Day. Many heart disease and stroke survivors have benefited from advances as a result of NIH-supported research. However, despite progress and promising research opportunities, there is still no cure for heart disease or stroke…

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Request For Re-Examination Of Ceftobiprole Submitted To CHMP

March 12, 2010

Basilea Pharmaceutica Ltd. (SWISS: BSLN) announces that the Applicant Janssen-Cilag International NV (Janssen- Cilag), a Johnson & Johnson company, has submitted a request for re-examination of the negative opinion by the European Committee for Medicinal Products for Human Use (CHMP) on the Marketing Authorization Application (MAA) for ceftobiprole for the treatment of complicated skin and soft tissue infections (cSSTI). On February 18, 2010, the CHMP adopted a negative opinion on the MAA for ceftobiprole for the treatment of cSSTI…

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Stem Cell Therapeutics Corp. Announces Publication Of Phase IIa Stroke Data

March 12, 2010

Stem Cell Therapeutics Corp. (“SCT” or the “Company”) (TSX VENTURE:SSS) wishes to announce the acceptance and publication of the paper entitled “The Beta-hCG + Erythropoietin in Acute Stroke ( BETAS) Study” by the journal “Stroke”, on March 8, 2010. This paper was authored by Dr. Steven C. Cramer, from the University of California, Irvine, Dr. David Brown at Hoag Memorial Hospital Presbyterian, New Port Beach, Dr. Michael D. Hill of Foothills Hospital at the University of Calgary, and colleagues. Dr…

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Wilson Disease

March 12, 2010

Wilson disease is an inherited condition that causes the body to retain excess copper. The liver of a person who has Wilson’s disease does not release copper into bile as it should. As the copper builds up in the liver, it begins to damage the organ.

After enough damage, the liver releases the copper directly into the bloodstream, which carries the copper throughout the body. The copper buildup leads to damage in the kidneys, brain, and eyes. If not treated, Wilson’s disease can cause severe brain damage, liver failure, and death.

What are the symptoms of Wilson disease?

Wilson… Continue reading

Medtronic Introduces The Vertex Select(R) Reconstruction System

March 12, 2010

Medtronic, Inc. (NYSE: MDT) announced the U.S. launch of the VERTEX SELECT® Reconstruction System. When a patient has a spinal condition that requires fusion or a procedure that must be performed from the back of the spine, also known as a posterior approach, the VERTEX SELECT® Reconstruction System contains implants and an instrument set for performing this surgical procedure. Conditions of the spine, such as degenerative disc disease, tumor, or trauma, can lead to instability and pain for patients…

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