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Black Children At Lower Risk Of Shingles After Chickenpox Vaccine; Genetic Explanation Is Most Likely, Researchers Think

March 17, 2010 Health News No Comments

Black children are less likely than white or Asian children to develop shingles (herpes zoster) after receiving the varicella vaccine to prevent chickenpox, reports a study in the March issue of The Pediatric Infectious Disease Journal. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health, a leading provider of information and business intelligence for students, professionals, and institutions in medicine, nursing, allied health, and pharmacy…

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Opening New Avenue For Developing Treatments For Genetic Muscle-Wasting Disease

March 17, 2010 Health News No Comments

Scientists from the Ottawa Hospital Research Institute (OHRI) and the University of Ottawa have identified a promising new approach for developing drugs to treat Spinal muscular atrophy (SMA), the leading inherited cause of death in infants and toddlers. Dr. Rashmi Kothary and his doctoral student Melissa Bowerman have found that an enzyme called RhoA is overly active in a mouse model of the disease and blocking this enzyme can greatly increase survival. The study is published in Human Molecular Genetics…

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Pediatrics Study By Autism Consortium Shows CMA Finds More Genetic Abnormalities Than Current Tests

March 16, 2010 Health News No Comments

The Autism Consortium, an innovative research, clinical and family collaboration dedicated to catalyzing research and enhancing clinical care for families with autism spectrum disorders (ASDs), announced today that the results of its comparison study of genetic testing methods for autism spectrum disorders is available from the journal Pediatrics through early online release in their eFirst pages and will appear in the journal’s April issue…

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New Analysis Assesses Impact Of Common Genetic Variation On Benefit Of Antiplatelet Therapy

March 16, 2010 Health News No Comments

A new analysis of the TRITON-TIMI 38 study evaluated response rates in patients with a common genetic variant in the ABCB1 gene. Patients enrolled in the TRITON-TIMI 38 study were treated with dual antiplatelet therapy with either Plavix® (clopidogrel) plus aspirin or Effient® (prasugrel) plus aspirin and managed with percutaneous coronary intervention (PCI) following an acute coronary syndrome (ACS) event. The results of this retrospective genetic sub-study were presented today at the American College of Cardiology annual meeting…

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Scientists Discover Causative Genetic Mutation Associated With Common Inherited Neurological Disorder

March 12, 2010 Health News No Comments

Scientists using advanced genomic analysis technologies from Life Technologies Corporation (NASDAQ: LIFE) have sequenced an individual’s genome and identified the specific causative mutation associated with Charcot-Marie-Tooth Disease (CMT), one of the most common inherited neurological disorders currently affecting 1 in 2,500 individuals in the United States. In a paper published today by The New England Journal of Medicine (NEJM), , Baylor College of Medicine doctors Richard Gibbs and James R…

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First Whole Genome Sequencing Of Family Of Four Reveals New Genetic Power

March 12, 2010 Health News No Comments

The Institute for Systems Biology (ISB) has analyzed the first whole genome sequences of a human family of four. The findings of a project funded through a partnership between ISB and the University of Luxembourg was published online today by Science on its Science Express website. It demonstrates the benefit of sequencing entire families, including lowering error rates, identifying rare genetic variants and identifying disease-linked genes. “We were very pleased and a little surprised at how much additional information can come from examining the full genomes of the same family…

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First Inherited Prostate Cancer Genetic Mutation Found In African-American Men

March 11, 2010 Health News No Comments

Shahriar Koochekpour, MD, PhD, Assistant Professor of Microbiology and Immunology, Biochemistry and Molecular Biology, and Genetics at LSU Health Sciences Center New Orleans, led research that has discovered, for the first time, a genetic mutation in African-American men with a family history of prostate cancer who are at increased risk for the disease. Dr. Koochekpour, who is also a member of the LSUHSC Stanley S…

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Researchers Identify Previously Unrecognized Genetic Disorder

March 11, 2010 Health News No Comments

Researchers from four laboratories that perform diagnostic genetic testing of chromosome abnormalities in individuals with unexplained physical and developmental disabilities recently identified a previously unrecognized genetic disorder…

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In U.S. Imaging First, Prenatal MRI Detects Rare Genetic Disease In Newborn

March 11, 2010 Health News No Comments

In a case believed to be a United States first, the radiology team at Lucile Packard Children’s Hospital has used prenatal magnetic resonance imaging to detect an often-misdiagnosed genetic disease. The disorder, congenital chloride diarrhea, can cause severe dehydration and serious metabolic disturbances in newborns if not treated quickly. “This is a disease where early diagnosis is the key to a good outcome,” said Richard Barth, MD, the physician who recognized the unusual case…

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Genetic Variant Greatly Increases Lung Cancer Risk For Light Smokers

March 10, 2010 Health News No Comments

Individuals with a certain type of genetic susceptibility to lung cancer face a greatly increased risk for the deadly disease with even a small exposure to cigarette smoke, a study team that includes researchers from the University of Cincinnati (UC) has concluded. For family members who carry this genetic variant, the risk of lung cancer is similar for both light and heavy smokers, the researchers say, adding that even non-smokers who are exposed to second-hand cigarette smoke and have a family history of lung cancer should be monitored for early detection…

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Melanoma Survivors Appear To Be At Increased Risk For Another Melanoma

March 18, 2010

Survivors of one melanoma appear approximately nine times as likely as the general population to develop a second melanoma. Porcia T. Bradford, M.D., and colleagues at the National Cancer Institute, Bethesda, Md., used nine cancer registries to identify 89,515 patients who survived at least two months after an initial melanoma diagnosis between 1973 and 2006. Of these, 10,857 (12.1 percent) developed one or more additional primary cancers, such that their overall risk of another cancer increased by 28 percent. One-fourth of these subsequent cancers were primary melanomas…

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Is Your Next Cruise Safe from the Norovirus?

March 18, 2010

Nothing quite dampens your cruise vacation like a little diarrhea or nausea, and that’s among the topics cruise line executives are discussing this week at the major Cruise Shipping Miami conference (formerly known as Seatrade).
Specifically, the issue is the dreaded norovirus, the fast-moving stomach bug that can quickly infect a ship (or, for that matter, a school, shopping mall or any other gathering of people). In fact, outbreaks occur in many places. So why do we hear about it so much in the news regarding cruise ships?
The reason cruise ships are watched so closely is because, as foreign-flagged vessels, they… Continue reading

Studies Reveal Substantial Increases In Non-Melanoma Skin Cancers

March 18, 2010

Both new diagnoses and a history of non-melanoma skin cancer appear to have become increasingly common, and the disease affects more individuals than all other cancers combined, according to two reports in the March issue of Archives of Dermatology, one of the JAMA/Archives journals. The article is one of several in the issue focusing on skin cancers, and is being published in conjunction with a JAMA theme issue on cancer…

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Historic Win As Senate Passes NP And Midwife Legislation, Australia

March 18, 2010

The Australian Nursing Federation has welcomed the decision to pass legislation giving nurse practitioners and eligible midwives access to MBS and PBS. ANF Federal Secretary Ged Kearney congratulated the senate on their decision to pass the Health Legislation Amendment (Midwives and Nurse Practitioners) Bill 2009 saying it was significant news and a major win for consumers. “The senate has passed long-awaited legislation that gives those who seek the services of nurse practitioners and eligible midwives access to benefits,” she said…

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Other Health Professions Need Support As Well – Pharmaceutical Society Of Australia

March 18, 2010

The Government’s announcement of a substantial boost in GP training places, specialist training places and pre-vocational general practice placements for medical graduates is a welcome development, but other health professions need similar support, the Pharmaceutical Society of Australia says. National President of the PSA, Warwick Plunkett, said that in moving to the Government’s preferred primary health-care team model, it was important the difficulties facing the other professions in the primary health-care team were also recognised and acted upon…

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The American Nurses Association Releases New Position Statements On Pivotal Topics Affecting Nursing Practice

March 18, 2010

The American Nurses Association (ANA), the largest nursing organization in the U.S., has approved two instructive and interpretive policy documents produced by its Congress on Nursing Practice and Economics (CNPE): a revised position statement entitled Nurses’ Role in Capital Punishment, and an initial position statement entitled Just Culture. “ANA takes very seriously its obligation to provide thought leadership and guidance to nurses everywhere on matters of significant professional and ethical consequence,” commented ANA President Rebecca M. Patton, RN, MSN, CNOR…

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FDA Orders 2 Companies To Stop Marketing Unapproved Nitroglycerin Tablets

March 18, 2010

The U.S. Food and Drug Administration today ordered Glenmark Generics of Mahwah, N.J., and Konec Inc. of Tucson, Ariz., to stop marketing unapproved nitroglycerin tablets. The tablets are placed under the tongue to relieve chest pain or to stop a heart attack and are marketed in 0.3 mg, 0.4 mg, and 0.6 mg dosages. The FDA does not anticipate a supply problem for these products. Pfizer Inc. markets FDA-approved sublingual nitroglycerin tablets in the same strengths and is able to supply the market with approved products…

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RCN Union Learning Representatives Host Motivational Day For Health Care Staff, Wales

March 18, 2010

The Royal College of Nursing in Wales in partnership with a local nurse from Abertawe Bro Morganwg Local Health Board has organised an event for health care staff working within the NHS and independent sector at the Aberavon Hotel, Port Talbot on Monday, 1 March, 2010. This event was sponsored by the Welsh Union Learning Fund. The event is a motivational seminar for health care staff and in the spirit of partnership, invitations have been offered to other local union members. A selection of inspirational speakers will feature throughout the day…

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