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GE Healthcare Announces New Compatibility For Fractional Flow Reserve (FFR) Evaluation With The Mac-Lab(R) XT And XTi Hemodynamic Recording Systems

March 20, 2010 Health News No Comments

GE Healthcare, the $17 billion medical technology division of General Electric Company (NYSE:GE), today announced the Mac-Lab’s validation of compatibility with the Volcano’s SmartMap® Pressure Instrument and PrimeWire® Pressure Guide Wire for evaluation of Fractional Flow Reserve (FFR). Coronary heart disease caused 425,425 deaths in 2006 and is the single leading cause of death in America today1. It is caused by atherosclerosis, the narrowing of the coronary arteries due to fatty build ups of plaque. It’s likely to produce angina pectoris (chest pain), heart attack or both…

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Centocor Ortho Biotech Products And Amgen Finalize ESA Risk Evaluation And Mitigation Strategy (REMS) With FDA

February 17, 2010 Health News No Comments

Centocor Ortho Biotech Products, L.P. and Amgen Inc. announced that the U.S. Food and Drug Administration (FDA) has approved the Risk Evaluation and Mitigation Strategy (REMS) for erythropoiesis-stimulating agents (ESAs), which include PROCRIT® (Epoetin alfa), Aranesp® (darbepoetin alfa) and EPOGEN® (Epoetin alfa)…

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Evaluation of a Neck Mounted 2-Hourly Activity Meter System for Detecting Cows About to Ovulate in Two Paddock-Based Australian Dairy Herds

January 23, 2010 Rectal Bleeding No Comments

Two studies were conducted to assess the performance of a commercially available neck-mounted activity meter to detect cows about to ovulate in two paddock-based Holstein-Friesian dairy herds. The activity monitoring system recorded cow activity count in 2-hourly periods. Study I investigated the ability of the system to detect cow ovulatory periods in dairy herds managed in two different Australian environments and breeding systems using five activity alert algorithms. Herd 1 consisted of approximately 130 milking cows calving year-round in a sub-tropical environment and kept in a single dry lot paddock. Herd 2 consisted of approximately 400 milking cows calving seasonally… Continue reading

Designing A Risk Evaluation And Mitigation Strategies (REMS) System

December 11, 2009 Health News No Comments

The Special Feature of the November/December 2009 issue of the Journal of the American Pharmacists Association JAPhA® is a “White paper on designing a risk evaluation and mitigation strategies (REMS) system to optimize the balance of patient access, medication safety, and impact on the health care system.” The paper results from the input of an expert panel of stakeholders convened by the American Pharmacists Association (APhA) to explore standardized solutions to REMS development and implementation…

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Dose-Escalation Using IMRT For Prostate Cancer – Evaluation Of The Dose Distribution Detected Simultaneous Integrated Boost

December 5, 2009 Health News No Comments

UroToday.com – Randomized three-dimensional conformal radiotherapy dose escalation studies have consistently shown improved biochemical control rates for prostate cancer. This benefit was associated with the problem of increased rectal toxicity. The increasing implementation of image-guided radiotherapy (IGRT) allows a reduction of safety margins around the clinical target volume (CTV). Thus, the same or improved local tumour control with lower rectal toxicity due to reduced rectal volume within the target volume can be expected…

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Is The Incidence Of Uretero-Intestinal Anastomotic Stricture Increased In Patients Undergoing Radical Cystectomy With Previous Pelvic Radiation?

December 1, 2009 Health News No Comments

In the online edition of the British Journal of Urology, the Department of Urology at the University of Miami reported on the impact of prior pelvic radiotherapy (XRT) on the occurrence of uretero-intestinal anastomosis (UIA) stricture at subsequent urinary diversion.

Pelvic XRT can potentially affect small blood vessels and induce tissue fibrosis. In patients who have not had prior pelvic XRT, the incidence of UIA stricture with urinary diversion ranges from 1% to 9%. This patient cohort was retrospectively identified at the University of Miami from 1992 to 2008. A total of 526 patients were identified, and of these… Continue reading

Bayer Starts Phase III Trial With Florbetaben

December 1, 2009 Health News No Comments

Bayer Schering Pharma AG, Germany, is progressing with the development of florbetaben to support Alzheimer diagnosis. On the occasion of the 95th Scientific Assembly and Annual Meeting of the Radiological Society of North America (RSNA), the company announced the enrollment of first patients in an international clinical Phase III trial to evaluate the efficacy and safety of florbetaben (BAY 94-9172) PET imaging in the detection of beta-Amyloid deposition in the brain. The trial will include both subjects with and without manifest dementia (e.g. Alzheimer’s disease [AD]). In the previous Phase II trial, florbetaben has successfully demonstrated its potential to detect… Continue reading

Effect Of Carbohydrate-Electrolyte Sports Beverages On Urinary Stone Risk Factors

December 1, 2009 Health News 1 Comment

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Designer waters are popular in the 21st century and many stone patients ask if they can consume their fluid intake with these products, such as Gatorade. We, as clinicians managing these stone patients, can now be reassured that this fluid is equivalent to water in their daily fluid consumption.

In this prospective, crossover study normal and hypercalcuric patients were placed on a monitored stone prevention diet for the entire duration of the study. The subjects then consumed 2 liters of Gatorade for one week and then 2 liters of water for one week and performed 24 hour… Continue reading

ArGentis Acquires Rights To Rheumatoid Arthritis Therapy Entering Phase I Clinical Trial

November 30, 2009 Health News No Comments

arGentis Pharmaceuticals, LLC announced that it will collaborate with the University of Tennessee Health Science Center (UTHSC) and the Veterans Affairs Medical Center of Memphis (VAMC) to initiate the first human clinical evaluation of an oral altered peptide ligand (APL), ARG301, in a Phase I study of Rheumatoid Arthritis patients.

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FDA’s Woodcock Discusses Pain Management And Drug Safety In Nov. 26, 2009 Issue Of The New England Journal Of Medicine

November 30, 2009 Health News No Comments

An article by Janet Woodcock, M.D., director of the FDA’s Center for Drug Evaluation and Research, titled “A Difficult Balance – Pain Management, Drug Safety, and the FDA,” appears in the Nov. 26, 2009 issue of The New England Journal of Medicine.

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Racial Disparity In Colon Cancer Survival Not Easily Explained

March 21, 2010

A new study by University of Alabama at Birmingham (UAB) researchers shows that body-mass index (BMI) and co-existing medical conditions (co-morbidity) do not explain the decreased survival observed among African-Americans compared to Caucasians who also have colon cancer. The study is published online Nov. 23 in Cancer, a journal of the American Cancer Society. (Source: Health News from Medical News Today) Go to Source… Continue reading

Pelosi Urged Obama To Not Cut Back On Health Care Plan

March 21, 2010

The New York Times recounts the steps Democrats took to regroup on the health overhaul legislation after losing their filibuster proof majority in the Senate after Massachusetts voters elected Republican Scott Brown in January. According to the Times account, House Speaker Nancy Pelosi helped steer President Barack Obama away from a more modest approach on health care. ‘“We’re in the majority,’ Ms. Pelosi told the president. ‘We’ll never have a better majority in your presidency in numbers than we’ve got right now. We can make this work,” the paper reported.”Now, in what could become a legislative Lazarus tale — or… Continue reading

Prader-Willi syndrome: a form of obesity that can be explained

March 21, 2010

Prader-Willi syndrome, also known as PWS is an uncommon genetic disorder (present at birth) in which seven genes (or subsets) on chromosome 15 are deleted or unexpressed. Patients with PWS may have physical, mental and behavioral problems – the main one being an unrelenting feeling of hunger.

Individual with Prader-Willi syndrome have serious problems controlling their body weight, because they spend much longer eating than other people do – there is a very strong food compulsion. PWS is the most common genetic cause of morbid obesity in children.

According to the Prader-Willi Association, USA, between 1 in 8,000 and 1 in 25,000… Continue reading

Public Health receives grants to fight obesity, tobacco use

March 21, 2010

The U.S. Department of Health and Human Services and the U.S. Centers for Disease Control and Prevention announced today that Public Health – Seattle & King County has been awarded two highly-competitive federal stimulus grants totaling $25.5 million dollars over two years to address obesity and tobacco use, two of the leading contributors to premature illness, death and health care costs in the United States and locally.

“It’s a huge credit to our Public Health staff and partners that we were able to get such a competitive grant to improve our community’s health,” said King County Executive Dow Constantine. Over 600… Continue reading

Stimulus money to help build healthier Hub

March 21, 2010

Boston has received $12.5 million in federal stimulus funding for a sweeping new effort to combat obesity and reduce smoking, Mayor Thomas M. Menino said yesterday.

Menino said the money, which would be spent over a two-year period, would be “a significant down payment on making Boston the healthiest city in America.’’

The city has a goal of reducing obesity rates by 20 and 30 percent in adults and children. respectively, over the next five years, and closing the gap between blacks and Latinos and whites. Go to Source… Continue reading

Omaha Gets Money to Fight Childhood Obesity

March 21, 2010

The U.S. Department of Health and Human Services is trying to combat the obesity problem by distributing over 372 million dollars in grants. Some of that money is being sent right here to Douglas County.

While a study shows obesity becoming more of a problem across the country, the stats in Douglas Country don’t paint a great picture either.

When it comes to the Omaha youth, the numbers become even more disturbing. But thanks to a 5.7 million dollar grant, Omahans will have a better chance to fight this problem head on. Go to Source… Continue reading

Emisphere Technologies And Alchemia To Research An Oral Formulation Of Fondaparinux With Eligen(R) Technology

March 21, 2010

Emisphere Technologies, Inc. (OTCBB:EMIS) and Alchemia Ltd. (ASX:ACL) announced that they are joining efforts to develop an oral formulation of the anti-coagulant drug fondaparinux with Emisphere’s Eligen® Technology. Emisphere’s broad-based drug delivery platform, known as the Eligen® Technology, uses proprietary, synthetic carriers to enhance the oral bioavailability of a drug without altering its chemical form or biological activity. Fondaparinux, an anti-coagulant used for the prevention of deep vein thrombosis, is marketed in injectable form as Arixtra® by GlaxoSmithKline…

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Emisphere Technologies And Alchemia To Research An Oral Formulation Of Fondaparinux With Eligen(R) Technology

March 21, 2010

Emisphere Technologies, Inc. (OTCBB:EMIS) and Alchemia Ltd. (ASX:ACL) announced that they are joining efforts to develop an oral formulation of the anti-coagulant drug fondaparinux with Emisphere’s Eligen® Technology. Emisphere’s broad-based drug delivery platform, known as the Eligen® Technology, uses proprietary, synthetic carriers to enhance the oral bioavailability of a drug without altering its chemical form or biological activity. Fondaparinux, an anti-coagulant used for the prevention of deep vein thrombosis, is marketed in injectable form as Arixtra® by GlaxoSmithKline…

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