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Anti-Hypertensive Drugs To Enhance Esophageal Contraction

March 8, 2010 Health News No Comments

Nifedipine, a calcium-channel blocker, was shown to decrease lower esophageal sphincter pressure and increase esophageal acid exposure time, while atenolol, a b1 blocker, was shown to inhibit relaxation of the smooth muscle of the esophagus. However, the influence of these anti-hypertensive drugs on the segment of esophageal body contraction using high-resolution manometry was not fully investigated. A research team from Japan observed esophageal body contraction using high-resolution manometry with 36 intraruminal transducers…

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When Drugs Cause Disease

March 6, 2010 Health News No Comments

The same drugs that are used effectively to treat diseases in millions of people around the world can sometimes be the cause of disease themselves. The American Society of Health-System Pharmacists (ASHP) has just released the 2nd edition of Drug-Induced Diseases: Prevention, Detection and Management, edited by James E. Tisdale, Pharm.D., BCPS, FCCP and Douglas A. Miller, Pharm.D. According to the authors, a drug-induced disease is an unintended effect of a drug, which results in illness with symptoms sufficient to prompt a patient to seek medical attention and/or require hospitalization…

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Cedars-Sinai Heart Institute Cardiologist Sanjay Kaul, M.D. Co-Authors Statement On Safety Of Diabetes Drugs

March 4, 2010 Health News No Comments

A Cedars-Sinai Heart Institute cardiologist co-authored the joint science advisory issued by the American Heart Association and the American College of Cardiology that calls for close monitoring of patients taking certain blood sugar-lowering drugs. Sanjay Kaul, M.D. co-authored the advisory about drugs called thiazolidinediones (TZDs) such as pioglitazone (Actos) or Rosiglitazone (Avandia)…

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Department Of Health And Children Statement In Relation To Legislation To Be Made Under Misuse Of Drugs Act 1977, Ireland

March 4, 2010 Health News No Comments

The Government agreed at its meeting on 2 March 2010 to the commencement of a notification process under Directive 98/34/EC (the “Technical Standards” Directive) as amended by Directive 98/48/EC of the Government’s intention to make a Declaration Order under the Misuse of Drugs Act 1977 declaring certain substances, products and preparations to be controlled drugs for the purposes of the Misuse of Drugs Acts, 1977 and 1984…

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New Model For Testing Anti-Alzheimer’s Drugs: At A Pier Near You

March 4, 2010 Health News No Comments

Alzheimer’s disease affects an estimated 27 million people worldwide. It is the most common form of age-related dementia, possibly the most feared disease of old age. There is no cure, and the available drugs only help to relieve symptoms without slowing progression of the disease. One of the characteristic changes in the brains of Alzheimer’s patients is the accumulation of plaques and tangles; currently, the best hope for curing or at least slowing the disease lies in developing drugs that target this buildup…

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Common Osteoporosis Drugs Are Associated With A Decrease In Risk Of Breast Cancer

March 3, 2010 Health News No Comments

Women who take some types of bone-building drugs used to prevent and treat osteoporosis may be at lower risk of breast cancer, according to a study by U.S. researchers published today in the British Journal of Cancer. The study found that women who used bisphosphonate drugs, such as Fosamax, Boniva and Zomita, for more than two years had a nearly 40 percent reduction in risk as compared to those who did not, according to lead author Polly Newcomb, Ph.D., M.P.H., head of the Cancer Prevention Program at Fred Hutchinson Cancer Research Center…

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Study Identifies Risks, Benefits Of Anemia Drugs

March 3, 2010 Health News No Comments

Aggressive treatment of anemia with intravenous iron and drugs known as erythropoiesis-stimulating agents (ESAs) may lower the risk of death for dialysis patients with severe anemia but also may increase the risk of death among patients with milder anemia, a new study led by a University of North Carolina at Chapel Hill epidemiologist suggests. Anemia is a common and often debilitating complication of kidney disease that has been linked to poor quality of life and increased risk of hospitalization and death…

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U.S. Food And Drug Administration (FDA) Sets 22 March For Oncologic Drugs Advisory Committee (ODAC) Meeting To Review OMAPRO™

March 3, 2010 Health News No Comments

ChemGenex Pharmaceuticals Limited (ASX:CXS) announced that the U.S. Food and Drug Administration (FDA) has rescheduled the previously postponed Oncologic Drugs Advisory Committee (ODAC) meeting to 22 March 2010. The ODAC meeting will consider ChemGenex’s application for OMAPRO™ (omacetaxine mepesuccinate) for the treatment of adults with chronic myeloid leukemia (CML) who have failed prior therapy with imatinib and who have developed the Bcr-Abl T315I mutation…

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Teva Gets 180-Day Headstart to Sell Generics of 2 Merck Drugs

March 3, 2010 Health News No Comments

In what could be a win-win decision for both Teva Pharmaceutical and Merck, a federal court said that Teva was entitled to six months of exclusivity to sell generic versions of two hypertension medicines made by Merck.
A district court ruled in July that Teva, the largest of the generic drug makers, had forfeited the 180 days of exclusivity that usually goes to the first applicant seeking FDA approval to make a generic versions of drugs — in this case, copycats of Merck’s Cozaar and Hyzaar.
But Teva said today an appeals court found the Israeli company should get the exclusive… Continue reading

Intracranial Stenting, Injecting Clot-Busting Drugs Directly To Brain May Be Better Than Other Treatments For Urgent Ischemic Strokes

February 26, 2010 Health News No Comments

Techniques that keep brain arteries open (intracranial stenting) or inject clot-busting drugs directly to the brain (intra-arterial tPA) may be more effective than other urgent ischemic stroke treatments, researchers said at the American Stroke Association’s International Stroke Conference 2010…

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Millennium Announces First Clinical Data For TAK-700 Prostate Molecule At ASCO GU

March 10, 2010

Millennium: The Takeda Oncology Company today announced the presentation of safety, pharmacokinetic and efficacy data from the Phase I portion of a Phase I/II clinical trial evaluating TAK-700 in patients with metastatic castration resistant prostate cancer (mCRPC). These data were presented at the American Society of Clinical Oncology Genitourinary Cancers Symposium (ASCO GU), held March 5-7, 2010 in San Francisco, CA…

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ImmunoGen, Inc. Announces Orphan Drug Designation Granted To IMGN901 For Treatment Of Merkel Cell Carcinoma By US FDA And EU COMP

March 10, 2010

ImmunoGen, Inc. (Nasdaq: IMGN), a biotechnology company that develops targeted anticancer products using its antibody expertise and Targeted Antibody Payload (TAP) technology, announced that the US Food and Drug Administration (FDA) has granted orphan drug designation to its IMGN901 compound when used for the treatment of Merkel cell carcinoma (MCC). Through a separate process, the European Union (EU) Committee for Orphan Medicinal Products (COMP) concurrently also granted IMGN901 orphan medicinal product designation for the treatment of MCC…

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BG Medicine And Abbott To Develop Galectin-3 Test For The I-STAT(R) System

March 10, 2010

BG Medicine, Inc. announced that it has entered into an agreement with Abbott Laboratories (NYSE: ABT) to extend its current development and commercialization collaboration to include the development of a galectin-3 test for Abbott Point of Care’s i-STAT® System. Galectin-3 is a novel biomarker that may play a role in detecting the development and progression of heart failure…

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Refresher: What’s In The Health Reform Bills

March 10, 2010

Since the Senate passed its version of a health overhaul on Christmas Eve, most of the debate has focused on the politics of the effort. By now, many people have forgotten — if they ever knew — what the bill would actually do.

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So here’s a short refresher. According to the Congressional Budget Office, the Senate-passed bill would expand coverage to roughly 30 million of the 46 million people in the U.S. who lack health insurance. Most of the remaining uninsured would be undocumented immigrants, who would be ineligible for benefits… Continue reading

InterMune’s Lung Drug Gets Backing From FDA Panel

March 10, 2010

Another day, another stock-price jump.
First, the preliminaries: An advisory panel this afternoon recommended the FDA approve a lung drug developed by InterMune, with majorities of the outside experts saying the proposed treatment appeared effective and safe.
The FDA is expected to decide by early May whether to go along with the panel’s recommendation on pirfenidone, which is intended to treat patients with idiopathic pulmonary fibrosis. The FDA usually follows the lead of its advisory committees.
This all comes as good news for investors in InterMune, whose shares streaked nearly 60% higher Friday because the questions posed by the FDA staff for today’s… Continue reading

Vets Welcome Extension To UK Pet Travel Protection

March 10, 2010

The European Parliament has voted 618 votes to 17 for an extension to the transitional arrangements contained within the regulation on the non-commercial movement of pet animals (Reg. 998/2003) which afford the UK additional protection against rabies, ticks and tapeworms. The British Veterinary Association (BVA) and British Small Animal Veterinary Association (BSAVA) have been lobbying MEPs to support the extension and have strongly welcomed this decision…

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Baby slings to get safety warning after deaths

March 10, 2010

The U.S. government is preparing a safety warning about baby slings — those popular and fashionable infant carriers that parents can sling around their chests to carry their baby. Go to Source… Continue reading

Britain may force owners to microchip dogs

March 10, 2010

British dog owners may be forced to microchip their pets and take out insurance, part of a proposed crackdown on the country’s dangerous canines. Go to Source… Continue reading

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