Home  »  Anal Fissure  »  Spiropyran-based optical approaches for mercury ion sensing: Improving sensitivity and selectivity via cooperative ligation interactions using cysteine.

Spiropyran-based optical approaches for mercury ion sensing: Improving sensitivity and selectivity via cooperative ligation interactions using cysteine.

 
 


Authors: Shao N, Gao X, Wang H, Yang R, Chan W
Spiropyrans are an attractive starting point in design of optical approaches for metal ions sensing. However, the high background in aqueous solution and non-specific chelation of the spiropyran with heavy metal ions has hindered their application as reliable sensors for environmental and biological species. Here, we report on a new spiropyran-based approach for sensitive and selective sensing of Hg(2+) in aqueous solution, based on cooperative ligation interactions among the spiropyran probe, an intermediate, cysteine, and the metal ion. To test the feasibility of this design, three spiropyran scaffolds, L1-L3, with different ligation functions at the 8′-position were examined as model systems. The results demonstrate that by using cystei… Go to Source

People who read this also read

Tags: , , , , , , , , ,

Write a Comment

Gravatars are small images that can show your personality. You can get your gravatar for free today!

«
»
Copyright © 2010 Procto Med. All rights reserved.