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Role of surgical management in temporal bone fibrous dysplasia.

Conclusion: Surgical treatment of fibrous dysplasia of the temporal bone (TBFD) revealed relatively good outcomes. Also, active surgical intervention is necessary to prevent the formation of secondary cholesteatoma or other complications. In particular, FD involving the inner ear may require greater caution when deciding on the resection area and timing of surgery. Objectives: The purpose of this study was to analyze clinical manifestations of TBFD and its surgical outcomes. Patients and methods: Nine patients diagnosed with TBFD after surgery at three tertiary referral centers were included. Pre- and postoperative clinical, audiological, and radiological findings were analyzed retrospectively. Results: Most patients… Continue reading

Late enhancement and myocardial perfusion in hypertrophic cardiomyopathy (comparison betw een groups)

CONCLUSION: The thickest ventricular segments are the septal ones. The hypertrophic regions are associated to a greater extension of late enhancement. There was a positive correlation between the areas of ventricular hypertrophy and altered myocardial perfusion and these findings were more evident in the obstructive group. (Source: Arquivos Brasileiros de Cardiologia) Go to Source… Continue reading

Pharmacogenetics of Asthma Therapy.

February 13, 2010 Gastric Obstruction No Comments

Authors: Duan QL, Tantisira KG
Asthma is a chronic disorder causing inflammation and reversible airway obstruction that affects approximately 300 million individuals worldwide. The incidence of asthma has nearly doubled in the past three decades resulting in higher rates of morbidity, mortality and health care costs. Despite the availability of several classes of asthma medications such as beta-agonists, leukotriene modifiers and corticosteroids, up to 50% of asthmatics do not benefit from one or more of these drugs. Studies have shown that asthma and drug response phenotypes such as forced expiratory volume in one second (FEV(1)) are heritable traits, indicating a… Continue reading

The Retrograde Aortic Arch in the Hybrid Approach to Hypoplastic Left Heart Syndrome [ORIGINAL ARTICLES: PEDIATRIC CARDIAC]

February 4, 2010 Gastric Obstruction No Comments

Conclusions
Clinically important RAAO occurred in 24% of the hypoplastic left heart syndrome patients in this series. If RAAO is detected at birth or early interstage, a Norwood operation is now favored. Palliative interventional catheterization remains very important mid and late interstage for continuing the hybrid strategy toward comprehensive stage 2. (Source: The Annals of Thoracic Surgery) Go to Source… Continue reading

Early and Intermediate Outcome After Anatomic Repair of Congenitally Corrected Transposition of the Great Arteries [ORIGINAL ARTICLES: PEDIATRIC CARDIAC]

February 1, 2010 Gastric Obstruction No Comments

Conclusions
Senning/arterial switch operations can be performed with excellent intermediate-term outcomes in patients with lesions previously thought to confer higher risk. Candidates for Senning/Rastelli procedures may be at increased risk for postoperative morbidity and mortality. More data are necessary to determine factors influencing outcome after anatomic repair. (Source: The Annals of Thoracic Surgery) Go to Source… Continue reading

Association of Interleukin-8 Gene Polymorphism With Cachexia From Patients With Gastric Cancer

Journal of Interferon & Cytokine Research , Vol. 0, No. 0: 1-10. (Source: Journal of Interferon) Go to Source… Continue reading

Importance of membrane-bound catechol-O-methyltransferase in L-DOPA metabolism: a pharmacokinetic study in two types of Comt gene modified mice

Conclusions and implications: In S-COMT-deficient mice, MB-COMT in the liver and the duodenum is able to O-methylate about one-half of exogenous L-DOPA. Sexual dimorphism and activity of the two COMT isoforms seems to be tissue specific and more prominent in peripheral tissues than in the brain. (Source: British Journal of Pharmacology) Go to Source… Continue reading

New gastric cancer drug approved

December 27, 2009 Gastric Obstruction No Comments

A drug to treat the seventh most common cancer in Europe has been approved by the European Medicines Agency (EMEA) (Source: Pharmacy Europe) Go to Source… Continue reading

Gastric outlet obstruction

December 22, 2009 Gastric Obstruction No Comments

Gastric outlet obstruction(GOO) is a medical condition manifested by obstruction at the level of the pylorus, which is the outlet of the stomach.

Causes of Gastric outlet obstruction

The causes are divided into Benign or malignant.

Benign Peptic ulcer disease, Bouveret’s syndrome is a rare cause of GOO is obstruction due to large gallstone . Pyloric stenosis is a cause of GOO in neonates. Infections, such as tuberculosis; and infiltrative diseases, such as amyloidosis.

Malignant Tumours of the stomach, including adenocarcinoma (and its linitis plastica variant), lymphoma, and gastrointestinal stromal tumours.
In a peptic ulcer it is believed… Continue reading

Vagus nerve stimulation-induced bradyarrhythmias in rats

December 19, 2009 Gastric Obstruction No Comments

Abstract: The autonomic consequences of seizures can be severe. Death can follow from autonomic overactivity that causes a parasympathetically mediated bradyarrhythmia. We studied the cardiovascular consequences of unilateral and bilateral stimulation of the distal segments of transected vagus nerve in rats anesthetized with urethane. The range of stimulation rates tested is comparable to the firing rates observed in vagus nerve during seizures. There was a consistent inverse relation between stimulus rate and heart rate with nodal block appearing at 5–10Hz and minimum HR levels (cardiac standstill) occurring at 50Hz. Cardiac standstill could last many seconds. Blood pressure during VNS was… Continue reading

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Congress, Obama Continue Health Reform Push

March 12, 2010

“Health care reform takes center stage Thursday as President Obama and top congressional Democrats work behind closed doors to nail down a final agreement,” CNN reports. House Speaker Nancy Pelosi, D-Calif., hosted a “meeting of the entire House Democratic caucus in the morning,” while Senate Majority Leader Harry Reid plans to hold a news conference that will “build public momentum by framing the issue in more personal terms.” Reid told reporters today that he believes progress is being made.  ”‘I really believe the goal we’ve been seeking for a long time of health care reform is going to be done. We don’t have… Continue reading

NHS Dental Charges In Wales Frozen Again

March 11, 2010

Dental patient charges in Wales have been frozen for the fourth year running to help maintain wider access to NHS dentistry, Health Minister Edwina Hart announced today [Thursday, 11 March]…

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Interacademy Council Asked To Review Intergovernmental Panel On Climate Change

March 11, 2010

The InterAcademy Council (IAC), a multinational organization of the world’s science academies, has been requested to conduct an independent review of the Intergovernmental Panel on Climate Change (IPCC) processes and procedures. The study comes at the invitation of the United Nations secretary-general and the chair of the IPCC, and will help guide the processes and procedures of the IPCC’s fifth report and future assessments of climate science…

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In Massachusetts, the Pros and Cons of New Imaging Technology

March 11, 2010

Fast-growing spending on imaging tests in Massachusetts gives a closeup view to the many-sided question of whether improved technology is really worth the extra cost.
The facts, as laid out by the Boston Globe this morning: Spending on MRIs, mammograms, and other imaging tests for privately insured Massachusetts residents jumped 20%, or $214 million, between 2006 and 2008, according to consultants hired by the state. Doctors ordering more tests was one reason for the added spending.
Digital mammography was another prime driver as some insurers pay more for these breast-screening tests and hospitals have invested upward of $400,000 for such new machines… Continue reading

Years of smoking associated with lower Parkinson’s risk, not number of cigarettes per day

March 11, 2010

Researchers have new insight into the relationship between Parkinson’s disease and smoking. Several studies have shown that smokers have a lower risk of developing Parkinson’s disease. A new study published in the March 10, 2010, online issue of Neurology®, the medical journal of the American Academy of Neurology, shows that smoking for a greater number of years may reduce the risk of the disease, but smoking a larger number of cigarettes per day may not reduce the risk.

“These results could guide the development of studies on various tobacco components with animal models to help understand the relationship between smoking and… Continue reading

NC State Research Tackles Childhood Obesity

March 11, 2010

Getting children involved in finding ways to become more physically active can not only make them more aware of local recreational opportunities, but can even help increase their own physical activity.

That’s the result of a study examining the role of seven national parks in contributing to the health of today’s youth. The study was conducted by researchers from a variety of disciplines at North Carolina State University and other U.S. universities and funded by the National Park Service.

The researchers developed pilot programs aimed at increasing the awareness of health benefits from participating in recreational activities at national parks and increasing… Continue reading

Smoking years key factor in lower Parkinson’s risk

March 11, 2010

Several studies have shown that smokers have a lower risk of developing Parkinson’s disease. A new study shows that it’s how many years of smoking a person has under their belt—rather than how much they smoke every day—that matters.

“Smoking is bad for you and no one should advocate smoking just for prevention of Parkinson’s,” Dr. Honglei Chen of the National Institute of Environmental Health Sciences in Research Triangle Park, North Carolina, one of the study’s authors, emphasized in comments to Reuters Health. But the findings could help researchers who are trying to figure out the underlying cause of the disease… Continue reading

Study says fat is the sixth “taste”

March 11, 2010

People sensitive to the taste of fat tend to eat less of it and are less likely to be overweight, according to Australian research that found human tongues can detect fatty tastes.

Researchers at Deakin University, working with colleagues at the University of Adelaide among others, found that fat was the sixth taste people can identify in addition to the five others – sweet, sour, salty, bitter and protein-rich.

In a statement, Deakin researcher Russell Keast said the findings build on previous research in the United States that used animal models to discover the taste for fat. Go to Source… Continue reading

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