Gastric Outlet Obstruction Overview

Gastric outlet obstruction (GOO) is not a single entity; it is the clinical and pathophysiological consequence of any disease process that produces a mechanical impediment to gastric emptying.

Clinical entities that can result in GOO generally are categorized into 2 well-defined groups of causes—benign and malignant. This classification facilitates discussion of management and treatment. In the past, when peptic ulcer disease (PUD) was more prevalent, benign causes were the most common; however, one review shows that only 37% of patients with GOO have benign disease and the remaining patients have obstruction secondary to malignancy.

GOO can be a… Continue reading

Is Short-Term Celecoxib Intervention A Effective Method For Preventing Gastric Carcinogenesis?

Since the isolation and culture of Helicobacter pylori (H. pylori) in 1983, this bacterium has become accepted as an important human pathogen for the development of gastritis, peptic ulcer, and gastric cancer. Cyclooxgenase-2 (COX-2) is a prostaglandin-synthesizing enzyme. Elevated expression of COX-2 is observed in a wide variety of human malignancies, including gastric cancer.  Go to Source… Continue reading

Henry Ford study: Drug used for neuropathic pain relieves discomfort from abdominal adhesions

(Henry Ford Health System) Pregabalin, FDA-approved for neuropathic pain (pain caused by shingles and peripheral neuropathy), effectively reduced abdominal pain and improved sleep in women with adhesions, according to a Henry Ford study. Adhesion pain, a common complication after abdominal or pelvic surgery, currently lacks effective therapy. Adhesions can also form after infections in the bowel such as diverticulitis. (Source: EurekAlert! – Medicine and Health) Go to Source… Continue reading

The Dangers of Hypochlorhydria (Low Stomach Acid)

What Are the Dangers of Hypochlorhydria?

Because the normal production of stomach acid is vital to the digestive process, and therefore the release of nutrients into the body, Hypochlorhydria can lead to many health issues. Food that is not broken down moves from the stomach, into the small intestine and colon, and then exits the body unutilized. In other words, you can eat to your heart’s content, but if you have Hypochlorhydria your body can reach starvation mode, and begin to display symptoms of nutrient deprivation. High acid levels are required for the break down of many trace minerals such… Continue reading

Maternal-fetal disease information as a source of exercise motivation during pregnancy.

Conclusion: Information grounded in PMT is effective in influencing pregnant women’s beliefs and intentions as well as changing their initial behavior. (PsycINFO Database Record (c) 2009 APA, all rights reserved) (Source: Health Psychology) Go to Source… Continue reading

About Gastroparesis

What is gastroparesis?

Gastroparesis, also called delayed gastric emptying, is a disorder in which the stomach takes too long to empty its contents. Normally, the stomach contracts to move food down into the small intestine for digestion. The vagus nerve controls the movement of food from the stomach through the digestive tract. Gastroparesis occurs when the vagus nerve is damaged and the muscles of the stomach and intestines do not work normally. Food then moves slowly or stops moving through the digestive tract.

What causes gastroparesis?

The most common cause of gastroparesis is diabetes. People with diabetes have high blood… Continue reading

Role of surgical management in temporal bone fibrous dysplasia.

Conclusion: Surgical treatment of fibrous dysplasia of the temporal bone (TBFD) revealed relatively good outcomes. Also, active surgical intervention is necessary to prevent the formation of secondary cholesteatoma or other complications. In particular, FD involving the inner ear may require greater caution when deciding on the resection area and timing of surgery. Objectives: The purpose of this study was to analyze clinical manifestations of TBFD and its surgical outcomes. Patients and methods: Nine patients diagnosed with TBFD after surgery at three tertiary referral centers were included. Pre- and postoperative clinical, audiological, and radiological findings were analyzed retrospectively. Results: Most patients… Continue reading

Late enhancement and myocardial perfusion in hypertrophic cardiomyopathy (comparison betw een groups)

CONCLUSION: The thickest ventricular segments are the septal ones. The hypertrophic regions are associated to a greater extension of late enhancement. There was a positive correlation between the areas of ventricular hypertrophy and altered myocardial perfusion and these findings were more evident in the obstructive group. (Source: Arquivos Brasileiros de Cardiologia) Go to Source… Continue reading

Remarkable high-yielding chemical modification of gold nanoparticles using uncatalyzed click-type 1,3-dipolar cycloaddition chemistry and hyperbaric conditions

Hossein Ismaili, Abdolhamid Alizadeh, Kristen E. Snell, and Mark S. Workentin – Azide-terminated alkyl thiolate monolayer-protected gold nanoparticles (1-C12MPN) with a core size of 1.8 ± 0.2 nm were prepared. 1-C12MPN was modified in high yields via an uncatalyzed 1,3-dipolar… (Source: Canadian Journal of Chemistry) Go to Source… Continue reading

Dilation of refractory benign esophageal strictures

Benign esophageal strictures are frequently encountered as a problem in endoscopic practice. Peptic injury, as a result of chronic exposure of the esophagus to gastric contents, is the most common cause of esophageal strictures, accounting for approximately 60% to 70% of cases. Other etiologies include Schatzki’s rings, esophageal webs, radiation injuries, caustic ingestions, photodynamic therapy-induced strictures, and anastomotic strictures. For centuries, the cornerstone of treatment for esophageal strictures has been dilation therapy. The first documented treatment dates back to 1674 when the passing of a whale bone through a stricture in the esophagus was reported. Since then, esophageal dilation devices… Continue reading